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his park2  (Sino Biological)


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    Structured Review

    Sino Biological his park2
    His Park2, supplied by Sino Biological, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/his+park2/Human+PARK2+Gene+ORF+cDNA+clone+expression+plasmid%2C+N-His+tag/pm35244772-324-12-14
    Average 91 stars, based on 1 article reviews
    his park2 - by Bioz Stars, 2026-09
    91/100 stars

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    Related Articles

    Transfection:

    Article Title: FKBP51 modulates hippocampal size and function in post-translational regulation of Parkin.
    Article Snippet: .. The cells were transfected with the Flag-Fkbp51 (HG11487-CF, Sino Biological, Beijing, China), His-Park2 (HG12092-NH, Sino Biological, Beijing, China) or HA-ubiquitin (#18712, Addgene, Cambridge, MA, USA) plasmid for overexpression or with the human Fkbp51 siRNA (sc-35380, Santa Cruz Biotech, Inc., Dallas, TX, USA) for knock-down, using Lipofectamine 3000 (L3000008, Life Technologies, Gaithersburg, MD, USA) according to the manufacturer’s recommendations. ..

    Article Title: FKBP51 Modulates Hippocampal Size and Function in Post-translational Regulation of Parkin
    Article Snippet: .. The cells were transfected with the Flag-Fkbp51 (HG11487-CF, Sino Biological, Beijing, China), His-Park2 (HG12092-NH, Sino Biological, Beijing, China) or HA-ubiquitin (#18712, Addgene, Cambridge, MA, USA) plasmid for overexpression or with the human Fkbp51 siRNA (sc-35380, Santa Cruz Biotech, Inc., Dallas, TX, USA) for knock-down, using Lipofectamine 3000 (L3000008, Life Technologies, Gaithersburg, MD, USA) according to the manufacturer’s recommendations. ..

    Plasmid Preparation:

    Article Title: FKBP51 modulates hippocampal size and function in post-translational regulation of Parkin.
    Article Snippet: .. The cells were transfected with the Flag-Fkbp51 (HG11487-CF, Sino Biological, Beijing, China), His-Park2 (HG12092-NH, Sino Biological, Beijing, China) or HA-ubiquitin (#18712, Addgene, Cambridge, MA, USA) plasmid for overexpression or with the human Fkbp51 siRNA (sc-35380, Santa Cruz Biotech, Inc., Dallas, TX, USA) for knock-down, using Lipofectamine 3000 (L3000008, Life Technologies, Gaithersburg, MD, USA) according to the manufacturer’s recommendations. ..

    Article Title: FKBP51 Modulates Hippocampal Size and Function in Post-translational Regulation of Parkin
    Article Snippet: .. The cells were transfected with the Flag-Fkbp51 (HG11487-CF, Sino Biological, Beijing, China), His-Park2 (HG12092-NH, Sino Biological, Beijing, China) or HA-ubiquitin (#18712, Addgene, Cambridge, MA, USA) plasmid for overexpression or with the human Fkbp51 siRNA (sc-35380, Santa Cruz Biotech, Inc., Dallas, TX, USA) for knock-down, using Lipofectamine 3000 (L3000008, Life Technologies, Gaithersburg, MD, USA) according to the manufacturer’s recommendations. ..

    Over Expression:

    Article Title: FKBP51 modulates hippocampal size and function in post-translational regulation of Parkin.
    Article Snippet: .. The cells were transfected with the Flag-Fkbp51 (HG11487-CF, Sino Biological, Beijing, China), His-Park2 (HG12092-NH, Sino Biological, Beijing, China) or HA-ubiquitin (#18712, Addgene, Cambridge, MA, USA) plasmid for overexpression or with the human Fkbp51 siRNA (sc-35380, Santa Cruz Biotech, Inc., Dallas, TX, USA) for knock-down, using Lipofectamine 3000 (L3000008, Life Technologies, Gaithersburg, MD, USA) according to the manufacturer’s recommendations. ..

    Article Title: FKBP51 Modulates Hippocampal Size and Function in Post-translational Regulation of Parkin
    Article Snippet: .. The cells were transfected with the Flag-Fkbp51 (HG11487-CF, Sino Biological, Beijing, China), His-Park2 (HG12092-NH, Sino Biological, Beijing, China) or HA-ubiquitin (#18712, Addgene, Cambridge, MA, USA) plasmid for overexpression or with the human Fkbp51 siRNA (sc-35380, Santa Cruz Biotech, Inc., Dallas, TX, USA) for knock-down, using Lipofectamine 3000 (L3000008, Life Technologies, Gaithersburg, MD, USA) according to the manufacturer’s recommendations. ..

    Knockdown:

    Article Title: FKBP51 modulates hippocampal size and function in post-translational regulation of Parkin.
    Article Snippet: .. The cells were transfected with the Flag-Fkbp51 (HG11487-CF, Sino Biological, Beijing, China), His-Park2 (HG12092-NH, Sino Biological, Beijing, China) or HA-ubiquitin (#18712, Addgene, Cambridge, MA, USA) plasmid for overexpression or with the human Fkbp51 siRNA (sc-35380, Santa Cruz Biotech, Inc., Dallas, TX, USA) for knock-down, using Lipofectamine 3000 (L3000008, Life Technologies, Gaithersburg, MD, USA) according to the manufacturer’s recommendations. ..

    Article Title: FKBP51 Modulates Hippocampal Size and Function in Post-translational Regulation of Parkin
    Article Snippet: .. The cells were transfected with the Flag-Fkbp51 (HG11487-CF, Sino Biological, Beijing, China), His-Park2 (HG12092-NH, Sino Biological, Beijing, China) or HA-ubiquitin (#18712, Addgene, Cambridge, MA, USA) plasmid for overexpression or with the human Fkbp51 siRNA (sc-35380, Santa Cruz Biotech, Inc., Dallas, TX, USA) for knock-down, using Lipofectamine 3000 (L3000008, Life Technologies, Gaithersburg, MD, USA) according to the manufacturer’s recommendations. ..



    Similar Products

    his park2  (Sino Biological)
    91
    Sino Biological his park2
    His Park2, supplied by Sino Biological, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/his+park2/Human+PARK2+Gene+ORF+cDNA+clone+expression+plasmid%2C+N-His+tag/pm35244772-324-12-14
    Average 91 stars, based on 1 article reviews
    his park2 - by Bioz Stars, 2026-09
    91/100 stars
    		  Buy from Supplier
    park2  (Sino Biological)
    91
    Sino Biological park2
    Increased Parkin levels occur in Fkbp51 KO mice via post-translational regulation. A Parkin expression is significantly increased in the Fkbp51 KO in the hippocampal subregions CA1 and DG, scale bar = 50 μm. B Primary cultured WT and Fkbp51 KO hippocampal neurons labeled at DIV9 with MAP2 (green), Parkin (red), and DAPI (blue), scale bar = 100 μm. WT neurons express more MAP2 but less Parkin than Fkbp51 KO neurons in the soma and dendrites. The magnified panel highlights the distinct labeling patterns in WT and Fkbp51 KO soma and dendrites. C Western blotting confirms significantly higher Parkin protein expression in the Fkbp51 KO hippocampus. Quantification of the western blot density indicates that the Parkin protein is significantly elevated in the Fkbp51 KO hippocampus (over 2.5-fold). D No significant differences were found in <t>Park2</t> mRNA expression. Data represent the mean ± SEM normalized to GAPDH. Pyr, pyramidal cell layer; Rad, radiatum layer; HR, hilar region; GCL, granule cell layer. Data represent mean ± SEM of 6 mice per genotype. P values were determined by Student’s unpaired t-test. ****P < 0.0001
    Park2, supplied by Sino Biological, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/his+park2/Human+PARK2+Gene+ORF+cDNA+clone+expression+plasmid%2C+N-His+tag/pmc11072506-666-14-16
    Average 91 stars, based on 1 article reviews
    park2 - by Bioz Stars, 2026-09
    91/100 stars
    		  Buy from Supplier

    Image Search Results


    Increased Parkin levels occur in Fkbp51 KO mice via post-translational regulation. A Parkin expression is significantly increased in the Fkbp51 KO in the hippocampal subregions CA1 and DG, scale bar = 50 μm. B Primary cultured WT and Fkbp51 KO hippocampal neurons labeled at DIV9 with MAP2 (green), Parkin (red), and DAPI (blue), scale bar = 100 μm. WT neurons express more MAP2 but less Parkin than Fkbp51 KO neurons in the soma and dendrites. The magnified panel highlights the distinct labeling patterns in WT and Fkbp51 KO soma and dendrites. C Western blotting confirms significantly higher Parkin protein expression in the Fkbp51 KO hippocampus. Quantification of the western blot density indicates that the Parkin protein is significantly elevated in the Fkbp51 KO hippocampus (over 2.5-fold). D No significant differences were found in Park2 mRNA expression. Data represent the mean ± SEM normalized to GAPDH. Pyr, pyramidal cell layer; Rad, radiatum layer; HR, hilar region; GCL, granule cell layer. Data represent mean ± SEM of 6 mice per genotype. P values were determined by Student’s unpaired t-test. ****P < 0.0001

    Journal: Cellular and Molecular Life Sciences: CMLS

    Article Title: FKBP51 modulates hippocampal size and function in post-translational regulation of Parkin

    doi: 10.1007/s00018-022-04167-8

    Figure Lengend Snippet: Increased Parkin levels occur in Fkbp51 KO mice via post-translational regulation. A Parkin expression is significantly increased in the Fkbp51 KO in the hippocampal subregions CA1 and DG, scale bar = 50 μm. B Primary cultured WT and Fkbp51 KO hippocampal neurons labeled at DIV9 with MAP2 (green), Parkin (red), and DAPI (blue), scale bar = 100 μm. WT neurons express more MAP2 but less Parkin than Fkbp51 KO neurons in the soma and dendrites. The magnified panel highlights the distinct labeling patterns in WT and Fkbp51 KO soma and dendrites. C Western blotting confirms significantly higher Parkin protein expression in the Fkbp51 KO hippocampus. Quantification of the western blot density indicates that the Parkin protein is significantly elevated in the Fkbp51 KO hippocampus (over 2.5-fold). D No significant differences were found in Park2 mRNA expression. Data represent the mean ± SEM normalized to GAPDH. Pyr, pyramidal cell layer; Rad, radiatum layer; HR, hilar region; GCL, granule cell layer. Data represent mean ± SEM of 6 mice per genotype. P values were determined by Student’s unpaired t-test. ****P < 0.0001

    Article Snippet: The cells were transfected with the Flag- Fkbp51 (HG11487-CF, Sino Biological, Beijing, China), His- Park2 (HG12092-NH, Sino Biological, Beijing, China) or HA-ubiquitin (#18712, Addgene, Cambridge, MA, USA) plasmid for overexpression or with the human Fkbp51 siRNA (sc-35380, Santa Cruz Biotech, Inc., Dallas, TX, USA) for knock-down, using Lipofectamine 3000 (L3000008, Life Technologies, Gaithersburg, MD, USA) according to the manufacturer’s recommendations.

    Techniques: Expressing, Cell Culture, Labeling, Western Blot